- Collaboration leverages BioNTech’s multi-platform immunotherapy capabilities and Medigene’s T cell receptor (TCR) discovery platform to discover and develop innovative TCR immunotherapies against targets selected by BioNTech
- BioNTech to acquire preclinical PRAME TCR and receive licenses to Medigene’s PD1-41BB switch receptor and precision pairing technologies
- BioNTech will hold exclusive worldwide development and commercialization rights to all TCR therapies arising from the collaboration
- Medigene will receive EUR 26 million upfront from BioNTech, as well as research funding, and will be eligible to receive development, regulatory and commercial milestone payments in addition to royalties and tiered deferred option payments on global net sales
Mainz/Martinsried/Munich, Germany, February 21, 2022 – BioNTech SE (Nasdaq: BNTX, “BioNTech”) and Medigene AG (FSE: MDG1, Prime Standard, “Medigene”), a clinical-stage immuno-oncology company focusing on the development of T cell immunotherapies, today announced that they have entered a multi-target research collaboration to develop T cell receptor (TCR) based immunotherapies against cancer. The initial term of the collaboration is three years.